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When looking for an erectile dysfunction (ED) medicine, men may tend to choose an option that offers the fastest results. The sooner the erection happens, the better, isn't it? The most common comparison for onset of action is between Sildenafil vs Tadalafil vs Avanafil tablets, as these are popular in the sexual wellness sphere. Viagra (Sildenafil), Cialis (Tadalafil), and Stendra (Avanafil) do ring a bell for anyone taking ED pills
So, let us understand which ED medication works fastest and how to choose between these alternatives.
Inhibitors of the enzyme phosphodiesterase-5 (PDE5) are often provided as treatment for aerectile dysfunction. They increase blood flow to the penile organ and relax its smooth muscles. The dilation of blood vessels helps the reproductive organ to keep blood in for longer and leads to a taut erection for several hours. However, the duration of how long an erection lasts after using an ED pill is one thing, while the fastest erectile dysfunction medication is a whole new experience in itself.
When it comes to which ED medication works fastest, Sildenafil or Viagra takes 30 to 60 minutes. The peak effect is seen within an hour, and a hard-on capacity may last for 4 to 6 hours. The common dosage strength is 25mg, 50mg, 100mg, and so on. For best results, take the medicine on an empty stomach and avoid heavy meals.
Make sure you are sexually stimulated as well. The pros include dependable medication with wide recall among people and years of trust, considerably fast onset, and availability of generics at a lower cost. The cons are that some people may experience blurry or tinted vision and slow action of the medicine if taken immediately after food.
The onset time for Tadalafil is 30 to 45 minutes. However, some can experience the effect as soon as 30 minutes. The peak effect is a couple of hours after the dosage and the erection duration is 24 to 36 hours. This is why Cialis is also known as the weekend pill. Dosing may start at 10mg, 20mg, and so forth. In some cases, a doctor may advise daily dosing as low as 2.5mg, 5mg, etc.
In terms of Sildenafil vs Tadalafil vs Avanafil, Cialis is not much impacted in efficacy when taken after food. The pros are evident, especially the longer time of erection ability and the facility of spontaneous erection during intimacy. Also, less food interaction is another benefit. The cons are a slower onset in contrast to Avanafil.
The clear winner for the fastest erectile dysfunction medication among the three discussed options is Avanafil. Its onset time is as little as 15 minutes. The peak work happens after 30 to 45 minutes of dosage, with an erection possibly lasting for 6 to 12 hours. You can take the medicine either after food or on an empty stomach. The standard doses are 50mg, 100mg, 200mg, etc.
The pros are a higher rate of satisfaction and successful intercourse because of the fast-acting effect, fewer medication interactions, and a lower chance of vision-related side effects. The cons may be a higher price due to better efficacy and faster action, and less widely available generics.
Here is a comparison table for Sildenafil vs Tadalafil vs Avanafil to denote which one works faster and the timing for lasting an erection:
| Medicine Name | Time Taken to Work | Peak Effect | Erection Duration |
|---|---|---|---|
| Stendra (Avanafil) | 15 to 30 minutes | 6 to 12 hours | 30 to 45 minutes after dosing |
| Viagra (Sildenafil) | 30 to 60 minutes | 4 to 6 hours | 1 hour after dosing |
| Cialis (Tadalafil) | 30 to 45 minutes | 24 to 36 hours | 2 hours after dosing |
By the above-mentioned details, we can say that Avanafil has the fastest onset, while Tadalafil offers the best duration for an erection to last. Factors that affect the time taken for an ED tablet to work include food intake. Fatty meals may delay the work of Sildenafil, but not so much for Tadalafil and Avanafil
Certain medicines may cause interactions, such as nitrates and HIV medicine, antibiotics, antifungals, etc. Alcohol and grapefruit are also not suitable combinations. Moreover, which ED medication works fastest also depends on your metabolism (liver and digestive function, kidney health, your age, etc.
Here are some factors to consider when selecting the fastest erectile dysfunction medication for yourself:
Understanding the Sildenafil vs Tadalafil vs Avanafil cost, where it is available, and if you may receive insurance coverage or not is a must-know. For instance, generics are widely available for Tadalafil and Sildenafil, which reduces medication costs. Since Stendra is newer, not many may know the generic for it. However, generic Avanafil has been available since 2018 at most places, especially from internet providers.
Insurance plans may not always cover all the ED medication options, so check the plan and coverage scope for the medicines you take. Some insurances cover generics rather than branded medications. It is possible for Avanafil to be costlier due to its faster onset. However, check out online pharmaceutical platforms, which may offer this medicine at a reduced cost.
Before choosing which ED medication works fastest, consider the following factors:
The fastest erectile dysfunction medication among Sildenafil, Tadalafil, and Avanafil may not always be the right option for your health and preference. Definitely it is, if you are focused on just an ED pill that gives the earliest results. However, you may want to compare cost, availability, safety, efficacy, duration of erection, side effect profile, food and medicine interactions, dosage norms, and other factors in consideration to select the apt ED tablet.
Stendra or Avanafil is the fastest working ED medication, as the onset of action is within 15 minutes and up to 30 minutes, compared to Sildenafil (30 to 60 minutes) and Tadalafil (30 to 45 minutes).
As discussed, take Avanafil at least 30 minutes before intercourse, while using Sildenafil at least an hour and Tadalafil 45 minutes before, respectively.
Yes, you can switch from one ED tablet to another depending on side effect tolerability, effectiveness, lifestyle needs, personal choice, and as per a physician’s recommendation.
All of the ED medicines discussed necessitate the presence of sexual stimulation for them to work. The PDE5 inhibitors only work if you are interested in intimacy and experience some physical engagement.
Avanafil may have fewer side effects, after which it is Tadalafil, followed by Sildenafil. So, you may compare the side effect possibility in the information listed above for better comparison.
It is best to avoid alcohol for any erectile dysfunction medicine you take. As for food, take Sildenafil on an empty stomach. Avoid fatty foods for all anti-ED pills. However, you can take Avanafil and Tadalafil with or without food.
While ED medicines have a proven track record, you can always enhance sexual function and erection by focusing on having a balanced diet, controlling weight, getting enough sleep, improving your relationship with your partner, cutting down on stress, and aiming for hormonal balance, adding zinc/minerals and other nutrients to meals, etc.